Table 1.
Summary of patients treated with concordant neurostimulation
| Report | Dx | No Perm | Resp Rate | Notes |
|---|---|---|---|---|
| Occipital Neuropathic Pain Treated with ONS Alone | ||||
| Weiner, Reed [12••] | ON | 13 | 80 % | 80 % had good to excellent relief |
| Rodrigo-Royo [21] | ON | 4 | 100 % | 97 % avg decrease in VAS |
| Kapural [16] | CEH | 6 | 100 % | 70 % avg decrease in VAS |
| Slavin [63] | ON | 10 | 70 % | All had excellent pain relief at 6 mo |
| Johnstone [15] | ON | 7 | 71 % | 73 % avg decrease in VAS |
| Melvin [17] | ON | 11 | 100 % | 73 % rated relief as good to excellent |
| Shaldi [64] | ON | 8 | 88 % | 71 % avg decrease VAS |
| Magown [65] | ON | 7 | 100 % | 6 had 75–100 % improvement |
| Vadivelu [66] | AC | 15 | 87 % | All had over 50 % improvement |
| Pameliere [19•] | NC | 8 | 100 % | 80 % avg relief |
| Oh [15] | ON | 10 | 100 % | All had 90–100 % relief |
| 89 % avg | ||||
| Trigeminal Neuropathic Pain Treated with Trigeminal Stim Alone | ||||
| Dunteman [23] | PHN | 1 | 100 % | SON |
| Johnson, Burchiel [25] | TNP | 10 | 70 % | I SON; 2 ION |
| Slavin [22•] | TNP | 7 | 82 % | 4 SON; 3 ION |
| Amin [24] | SON | 10 | 100 % | SON |
| Yakolev [26] | AFP | 2 | 100 % | Subcu octrodes over mandible |
| Stidd [27] | TNP | 3 | 100 % | 1 SON; 2 SON-ION |
| 88 % avg | ||||
| Occipitally-Focused Migraine Headaches Treated with ONS Alone | ||||
| Popeney [20••] | TM | 25 | 100 % | 100 % responded |
| Oh [18] | TM | 10 | 90 % | 90 % had >75 % improvement at 3–6 mo |
| Matharu [54••] | CM | 8 | 100 % | 100 % had good to excellent relief |
| 98 % avg | ||||
| Frontal (Cluster) Headaches Treated with Trigeminal Stim Alone | ||||
| Narouze [43•] | Cl | 1 | 100 % | SON stim |
| Vaisman [44•] | Cl | 5 | 100 % | SON stim |
| Simopoulos [67] | CM | 1 | 100 % | ATN stim |
| 100 % avg | ||||
| Hemicephalic/global (Chronic Migraine Headaches) Treated with Combined Stim | ||||
| Reed [45••] | CM | 7 | 100 % | ON-SON stim |
| Desphande [46•] | CM | 1 | 100 % | ON-ATN stim |
| Mammis [47•] | Cl | 1 | 100 % | ON-SON-ION stim |
| Reed [54••] | CM | 44 | 87 % | ON-SON stim |
| 89 % avg | ||||
| Summary: 93 % average response rate for all studies | ||||
ON occipital neuralgia; TM transformed migraine; CEH cervicogenic headaches; Dx diagnosis; IC2H Intractable C-2 Headaches; AC Arnold-Chiari; CM chronic migraine; ATN Auriculotemporal Nerve; ION infraorbital nerve; SON supraorbital nerve
Unless otherwise specified, all success rates indicate >50 % improvement in VAS or HA frequency