Table 2.

Patient Information of the Samples Used for Primary Cell Cultures and Treatments^a

Patient	Sex	Age, y	Type	Location	Genetic Background	Biochemistry	Inhibition at 1μM AZD8055, %	Inhibition at 3μM AZD8055, %
1	F	44	P	Right adrenal	Sporadic	NE, DA, NMN	27.1	48.5 (Torin-1, 48.2)
2	F	28	P	Right adrenal	SDHB	NE, DA, NMN, CgA	22.6	68.9
3	F	47	P	Right carotid body	Sporadic	CgA	23.2
4	M	5	P	Left adrenal	VHL	MN, NMN	17.1	51.9 (Torin-1, 52.4)

Abbreviations: CgA, chromogranin A; DA, dopamine; F, female; M, male; MN, metanephrine; NE, norepinephrine; NMN, normetanephrine; P, primary.

^aIncluded are the percent inhibition with 1 μM and 3 μM AZD8055 and 3 μM Torin-1.