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. 2013 Jan;52(1):70–77.

Table 1.

Summary of leukapheresis procedures in rhesus macaques

Macaque Weight (kg) Mobilizing agent(s) Dose(s) Blood volume given before leukapharesis (mL) Duration of procedure (min) No. of CD34+ cells recovered (× 106) Total no. of cells (× 109) No. of PBMC per kg of donor weight (× 108) Total volume collected (mL)
S0109 5.2 GCSF 10 μg/kg 125 240 6.5 12 30
S0509 5.3 GCSF 10 μg/kg 130 240 1.86 2.24 4.2 62
S0309A 8.1 GCSF 10 μg/kg 194 240 1.5 1.9 60
S0309B 8.8 GCSF 100 μg/kg 210 260 4.8 5.4 30
S9010 4.7 G-CSF 100 μg/kg 110 280 1.41 1.5 3.2 69
S0510 5.3 GCSF + AMD 3465 100 μg/kg, 1mg/kg 127 240 5.16 2.0 3.7 62
S0910 4.0 GCSF + AMD 3465 100 μg/kg, 1 mg/kg 96 275 1.7 4.2 85
S8810 3.9 GCSF + AMD 3465 100 μg/kg, 1 mg/kg 90 300 1.19 2.0 5.1 48
S8610 5.4 GCSF + AMD 3465 100 μg/kg, 1 mg/kg 129 300 1.5 2.7 57

There were no significant differences between treatment groups in the total number of cytokine-mobilized PBMC recovered.