Figure 7.

(A) MTT assay for cytotoxic assessment in MCF-7 cell line. Cytotoxicity effect of different concentration of empty capsules (free CS-HP), doxorubicin-loaded nanocapsules (CS-HP-DOX), and free-doxorubicin were checked using MTT assay. Data represents mean ± standard deviation. (B) Biodistribution studies done by injecting a single dose of 10 mg/kg doxorubicin in free form and encapsulated in nanocapsule. Serum was collected at different time periods and doxorubicin concentration was measured.

Abbreviations: CS, chitosan; DOX, doxorubicin; HP, heparin.