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De novo mutations observed with parental origin assigned
| Number of de novo mutations in proband | |||||
|---|---|---|---|---|---|
| Father's Age (yrs) |
Mother's Age (yrs) |
Paternal Chromosome |
Maternal Chromosome |
Combined | |
| Trio 1 | 21,8 | 19.3 | 39 | 9 | 48 |
| Trio 2 | 22.7 | 19.8 | 43 | 10 | 53 |
| Trio 3 | 25.0 | 22.1 | 51 | 11 | 62 |
| Trio 4 | 36.2 | 32.2 | 53 | 26 | 79 |
| Trio 5 | 40.0 | 39.1 | 91 | 15 | 106 |
| Mean | 29.1 | 26.5 | 55.4 | 14.2 | 69.6 |
| SD | 8.4 | 8.8 | 20.7 | 7.0 | 23.5 |
| Variance | 70.2 | 77.0 | 428.8 | 48.7 | 555.3 |
