Table 3.

Categorization of transplanted ESNP-derived neurons based on electrophysiological properties

Parameter	Type I (10)	Type II (4)	Type III (11)	Type IV (4)	Type V (1)	GIN (5)	p < 0.05
Membrane potential (mV)	−48.50 ± 2.4	−52.3 ± 3.1	−49.4 ± 2.5	−58.0 ± 2.7	−68	−44.7 ± 2.6
Delay to spike (ms)	19.7 ± 4.2	15.2 ± 6.1	18.0 ± 3.9	12.7 ± 4.3	44.2	16.6 ± 4.2
Spike threshold (mV)	−38.7 ± 1.7	−39.0 ± 4.0	−40.8 ± 2.3	−40.8 ± 4.3	−22.5	−41.8 ± 1.2
AP amplitude (mV)	67.1 ± 2.9	29 ± 2.6	63 ± 3.9	62 ± 6.2	31.3	59.5 ± 6.0	I–II,
							II–III,
							II–IV, II–GIN
AP half-width (ms)	0.82 ± 0.06	1.13 ± 0.43	1.04 ± 0.1	0.78 ± 0.09	2.1	0.96 ± 0.1
AP drop (mV)	6.0 ± 1.4	−2.3 ± 0.4	7.1 ± 1.6	3.2 ± 1.4	4.5	0.8 ± 1.2	I–II,
							II–III
Maximum frequency (Hz)	46.5 ± 3.2	50.7 ± 12.3	50.4 ± 8.1	55.2 ± 8.7	18.4	69.9 ± 17.6
Maximum number of APs	19.4 ± 2.4	24.5 ± 6.0	9.5 ± 1.0	25.8 ± 5.0	8	20.3 ± 6.7	I–III,
							II–III,
							III–IV
Adaptation	2.0 ± 0.2	2.2–0.3	2.3 ± 0.3	2.1 ± 0.2	2.3	1.6 ± 0.3
AHP1 amplitude (mV)	−18.1 ± 2.6	−7.9 ± 1.6	−15.0 ± 2.0	−16.6 ± 1.9	−9.3	−11.6 ± 1.8
AHP2 amplitude (mV)	−4.1 ± 0.9	−6.1 ± 2.3	−0.7 ± 0.7	−3.3 ± 1.2	0	−1.6 ± 1.6	II–III
Voltage sag ratio	1.47 ± 0.08	1.63 ± 0.26	1.01 ± 0.01	1.03 ± 0.03	1	1.17 ± 0.07	I–IV,
							I–III,
							II–III,
							II–IV, II–GIN
Input resistance (MΩ)	717 ± 98	450 ± 51	784 ± 107	641 ± 92	377	529 ± 83