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. 2013 Jan 15;10(1):e1001362. doi: 10.1371/journal.pmed.1001362

Table 1. Description of trials of smoking cessation interventions. Health behaviour change: smoking-related studies.

Study Study Design, Country, Device, Media Participants Aims Intervention Comparator
Free 2011 [36] Parallel group RCT; Country: UK; Device: Mobile telephone; Media: SMS 5,800 adult smokers aged ≥16 y. Mean age: 36.8 5 y (SD 11.05). Female 45% To evaluate the effect of mobile phone-based SMS support on the point prevalence of smoking at 6 mo. Participants received daily SMS before the quit date, then 5 SMS per day for 4 wk after the quit date. Between 4 and 26 wk participants received 3 SMS per week. Message content was tailored to participant interests and concerns about quitting smoking. Participants were offered a quit buddy contactable by mobile phone and an SMS craving helpline with an instant SMS response. The SMS system was fully automated. Duration: 26 wk. Participants received fortnightly simple, short, generic SMS
Free 2009 [112] Parallel group RCT; Country: UK; Device: Mobile telephone; Media: SMS 200 adult smokers aged ≥16 y. Mean age: 36 y (SD 9.0). Female 38% To evaluate the effect of mobile phone-based SMS support on the point prevalence of smoking at 4 wk. Participants received daily SMS before the quit date, then 5 SMS per day for 4 wk after the quit date. Between 4 and 26 wk participants received 3 SMS per week. Message content was tailored to participant interests and concerns about quitting smoking. Participants were offered a quit buddy contactable by mobile phone and an SMS craving helpline with an instant SMS response. The SMS system was fully automated. Duration: 26 wk. Participants received fortnightly simple, short, generic SMS.
Haug 2009 [113] Parallel group RCT Country: Germany; Device: Mobile telephone; Media: SMS 174 adult smokers. Mean age: Control 25.4 y (SD 4.9); Intervention 1 (1 SMS) 25.2 y (SD 4.8); Intervention 2 (3 SMS) 24.3 y (SD 3.8). Females: Control 63%; Intervention 1 56%; Intervention 2 52%. Investigate the feasibility and acceptability of interactive mobile phone text messaging to support smoking cessation and the impact of different SMS frequency (intensity). Participants received a weekly SMS with a question to assess their stage of change (transtheoretical model). Two intervention groups then received either 1 (1 SMS group) or 3 (3 SMS group) tailored feedback SMS per week. Participants attempting to quit had access to an SMS craving helpline which provided up to 60 tailored SMS responses. The SMS-COACH programme was fully automated. Duration: 14 wk Participants received only the weekly SMS question to assess their stage of change (transtheoretical model).
Rodgers 2005 [39] Parallel group RCT Country: New Zealand; Device: Mobile telephone; Media: SMS 1.705 adult smokers aged ≥16 y. Mean age 25 y. Female 58%. Assess the efficacy of SMS for supporting smoking cessation. Participants set a quit date and received 5 SMS per day for 1 wk before and 4 wk after the quit date. Between 4 wk after the quit date and the end of the study (26 wk) participants received 3 messages per week. SMS contained information or advice on quitting smoking and some distractions (e.g.. sports news, quizzes. and polls/surveys). Participants received 1 mo of free outgoing text messages after their quit date. Participants were offered a quit buddy (another study participant) contactable by mobile telephone. Participants had access to an SMS craving helpline to receive an instant reply with tips on cravings. The SMS system was fully automated and a computer algorithm was used to match the SMS sent to the participant characteristics. Duration: 26 wk. Participants only received one text message every 2 wk, thanking them for being in the study, providing study centre contact details, informing them that those who completed follow-up would be rewarded with a free month of text messaging (whether they quit or not), and reminding them of the time until their free month at the end of follow-up.
Vidrine 2006 [114] Parallel group RCT Country: USA; Device: Mobile telephone; Media: Voice 95 HIV positive adult smokers aged ≥18 y. Mean age: Control 43.1 y (SD 8.1); Intervention 42.6 y (SD 8.2). Females: Control 17%; Intervention 27.1%. Assess the efficacy of a mobile telephone smoking cessation counselling intervention aimed at a multiethnic, economically disadvantaged HIV-positive population. Participants set a quit date with their physician and received a personalized smoking cessation plan and a general self-help materials. Participants were given a prepaid mobile telephone and received 8 phone-counselling sessions during 2 mo. The counselling sessions were more often close to the quit date. Participants could also call the hotline when they needed additional smoking cessation support. The phone counselling and support was provided by a study researcher. Duration: 3 mo. Participants received usual care: they set a quit date with their physician who offered a 10-wk supply of nicotine replacement therapy and received the personalized smoking cessation plan and a general self-help materials.

RCT, randomized controlled trial; SD, standard deviation.