Table 1.
Performance on disulfide connectivity prediction obtained with correlated mutation measures
| # bonds | ICOV | MIp | Random | |||
|---|---|---|---|---|---|---|
| Pb = Rb | Qp | Pb = Rb | Qp | Pb = Rb | Qp | |
| 2 | 62 | 62 | 68 | 68 | 33 | 33 |
| 3 | 52.6 | 42.4 | 47.8 | 37.7 | 20 | 7 |
| 4 | 51.8 | 26.8 | 49.4 | 29.3 | 14 | 1 |
| 5 | 39.5 | 16.2 | 33.5 | 13.5 | 11 | 0.1 |
| All | 51.7 | 43.7 | 49.9 | 44.5 | 23 | 15 |
#bonds: number of disulfide bonds; iCOV: sparse inverse COVariance estimation; MIp: MIp: corrected Mutual Information. Random: performance obtained by a random predictor. Here Pb = Rb since the total number of predicted bonds (which is known in this experiment) is equal to the total number of observed bonds (Np = Nb). For index definition see Performance measures.