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Changes in the serum autoantibody level to SH3GL1 in a rat brain tumor model using C6 rat glioblastoma cells which were confirmed to express SH3GL1 protein. MRI studies show a steady growth of tumor mass in the rat brain (A). The serum autoantibody levels were significantly increased at 2-week after tumor inoculation, and tended to decrease at 4-week after the inoculation (B).
