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. 2013 Jan 18;8(1):e54587. doi: 10.1371/journal.pone.0054587

Table 1. Costs of components associated with diagnosis and treatment of drug sensitive, multi-drug resistant and extensively drug resistant tuberculosis.

Cost Component Cost ($US) Source
Inpatient stay (per day) BCH expenditure reports, Department of Health, BCH statistical reports, staff interviews
Capital costs (Buildings and Equipment) $4.70
Nursing & Medical staff $18.42
Support staff (OT, PT, Dietician, Psychologist, Data Capturer, etc) $4.77
Administrative staff $2.93
Staff overhead (excluding administrative staff) $7.20
Ancillary (Kitchen & Laundry) $9.23
Recurrent medical consumables $3.91
Non personnel recurrent overheads (utilities and other general supplies) $4.93
Total $56.07
Outpatient visit (per visit) BCH expenditure reports, Department of Health, BCH statistical reports, staff interviews
Capital costs (Buildings and Equipment) $1.59
Nursing & Medical staff $6.13
Support staff (OT, PT, Dietician, Psychologist, Data Capturer, etc.) $7.15
Administrative staff $0.97
Staff overhead (excluding administrative staff) $2.39
Recurrent medical consumables $1.30
Non personnel recurrent overheads (utilities and other general supplies) $1.64
Total $21.16
Clinic visit (per visit) Langa and Chapel St Clinic expenditure reports, Cape Town City Health, clinic staff interviews
Capital costs (Buildings and Equipment) $0.61
Staff (Nursing, Medical and General administrative staff) $4.44
Recurrent medical consumables $0.90
non personnel recurrent overheads (utilities and other general supplies) $0.69
Total $6.64
10 minute DOTS worker visit (per visit) $1.10 Provincial government salary scales
Drugs BCH pharmacy, Cape Town City Health
DS-TB
2 mth Intensive (RHZE) $16.77
4 mth Continuation (RH) $20.96
DS-TB Retreatment
3 mth Intensive (RHZES) $135.45
5 mth Continuation (RHE) $53.03
MDR-TB
6 mth Intensive (Km-Z-Mxf-Eto-Trd) $1,438.03
18 mth Continuation (Z-Mxf-Eto-Trd) $3,671.48
XDR-TB Primary
6 mth Intensive (Cm-Z-Mxf-Eto-Trd-PAS-Cfz) $5,272.91
18 mth Continuation (Cm-Z-Mxf-Eto-Trd-PAS-Cfz) $15,015.62
XDR-TB Acquired
6 mth Intensive (Cm-Z-Mxf-Clm-Aug-hdH-PAS-Cfz) $4,884.80
18 mth Continuation (Z-Mxf-Clm-Aug-hdH-PAS-Cfz) $13,406.14
Tests National Health Laboratory Services, Groote Schuur Hospital, WHO
Auramine Fluorescent Smear Microscopy $3.71
MGIT 960 liquid Culture $14.02
Xpert MTB-RIF $21.39
1st line DST (Line Probe Assay) $26.74
2nd line DST for 4 drugs (MGIT 960 liquid culture) $37.83
Chest X-ray $31.91
Audiogram $25.60
Liver function (Potassium, Urea, Creatinine) $15.05
Kidney function (ALT, AST, Bilirubin) $10.86
Thyroid function $20.89
HIV Rapid screening test $5.26
Other HIV associated tests (CD4 count, viral load) $51.75
Specimen transport Department of Transport, BCH expenditure reports, staff interviews
Capital $0.28
Recurrent cost $1.03
Personnel $1.40
Total $2.72
Surgery Groote Schuur Hospital
Pneumonectomy $5,549.36
Death i.e. Removal of body from premises $70.92 BCH financial department

DS-TB - Drug sensitive tuberculosis, MDR-TB – Multi-drug resistant tuberculosis, XDR-TB – Extensively Drug-resistant tuberculosis, ADR - Adverse Drug reaction, OT - Occupational Therapist, PT - Physiotherapist, BCH – Brooklyn Chest Hospital, DOTS – Directly Observed Treatment Short Course, MGIT – Mycobacterial Growth In-tube, DST – Drug susceptibility test, AST - aspartate aminotransferase, ALT - alanine aminotransferase, R - Rifampicin, H - Isoniazid, Z - Pyrazinamide, E - Ethambutol, S - Streptomycin, Km – Kanamycin, Mxf - Moxifloxacin, Eto - Ethionamide, Trd – Terizidone, Cm - Capreomycin, PAS – para-amionsalicylic acid, Cfz – Clofazimine, Clm-Clarithromycin, Aug - Augmentin, hdH - high dose Isoniazid.