Figure 7.

Confidence, c, panels for $\Delta H_{f,g}$ (left column) and $\Delta I_{f,\infty }$ (right column) for all groups used in our study. (A) MDA 435-implanted mice injected with ${\alpha }_v{\beta }_3$-targeted nanoparticles ($N=5$), (B) MDA 435-implanted mice injected with non-targeted nanoparticles ($N=5$), (C) MDA 435-implanted mice injected with saline ($N=5$), (D)–(F), same injections into $N=5$ tumor-free mice. The smoothing spline parameter $S=1.0$ in all cases. A color-to-confidence calibration bar is shown to the right of the confidence panels.