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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: J Spinal Disord Tech. 2013 May;26(3):E86–E94. doi: 10.1097/BSD.0b013e31826e0ca4

Figure 4. Hyaluronan synthase is upregulated more in moderately degenerated cells, while Biglycan is upregulated more in severely degenerated cells.

Figure 4

qRT-PCR results for hyaluronan synthase 1 (HAS1) and biglycan (BGN). Student's t-test indicated a significant difference from day 0 represented by a *. A two way ANOVA was performed with degeneration and media condition as factors, with the results shown in the upper right corner for each gene. Treatment groups with different letters are significantly different (Fisher's post hoc test α=0.05 was run for each media condition with pooled degenerative grades or when there was a significant interaction between media and degeneration a post hoc test was run with all six groups). ∼ indicates the gene was not expressed by that group. Significance was always defined as p<0.05, error bars represent SEM.