Figure 2.
The c-FOS locus is regulated by novel VDR/RXR binding. c-FOS genomic locus (chr14:74,787,306–74,820,798). ChIP-seq tag density profiles for VDR-Veh, VDR-1,25D3, SRC1-1,25D3, CBP-1,25D3, MED1-1,25D3, NCoR-1,25D3, SMRT-1,25D3, and input in the presence of 1,25(OH)2D3 are displayed centered around the c-FOS locus with gene transcriptional direction indicated by the arrow. The ChIP-seq tag densities have been normalized to 1×107 tags with the tag maximum for the data depicted on the top left of each track. FDR threshold of 0.001 is represented as a dashed line for each tag density track.