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. Author manuscript; available in PMC: 2014 Jan 15.
Published in final edited form as: Cancer Res. 2012 Nov 30;73(2):529–538. doi: 10.1158/0008-5472.CAN-12-3461

Figure 5.

Figure 5

Analysis of relevant enzyme expression/activity and transporter expression in the 3 cell lines. (A) mRNA expression of lactate dehydrogenase A (LDHA) and monocarboxylate transporters 1 and 4 (MCT1 and MCT4), relative to internal beta-actin expression, in the 3 cell lines (N=6 each). (B) LDH activity as measured by Km (μmols Pyruvate/106 cells) and Vmax (μmols NADH/sec/106 cells) in the 3 cell lines (N= 6 each). All values are reported as mean ± std. err. * denotes significant difference (p<0.05).