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PKC-dependent stimulation of renin in rat inner medullary collecting duct primary cultured cells. Relative abundance of prorenin protein in response to Ang II, Ang II + calphostin C, and PMA (phorbol 12-myristate 13-acetate) treatments in freshly isolated inner medullary collecting duct (IMCD) cells assessed by Western blot and immunofluorescence.*P<0.05 versus vehicle treated cells (adapted from Gonzalez et al. 2011)
