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. Author manuscript; available in PMC: 2014 Jan 15.
Published in final edited form as: Cancer Res. 2012 Nov 16;73(2):930–941. doi: 10.1158/0008-5472.CAN-12-1389

Figure 1. Ectopic expression of ZMIZ1 induces T-ALL in collaboration with NOTCH1.

Figure 1

Mice were reconstituted with 5FU-treated donor BM cells after transduction with indicated retrovirus. Representative flow cytometric analysis of peripheral blood of a NGFR/L1601PΔP mouse (A) and a ZMIZ1/L1601PΔP mouse (B). (C) Kaplan-Meier curves showing the fraction of mice without T-ALL after bone marrow transplantation. 6–8 mice per group. (D) Representative flow cytometric analysis of CD4/CD8 expression of a ZMIZ1/L1601PΔP mouse with T-ALL. Negative, non-transduced controls are shown (NGFR− GFP− cells).