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. 2012 Dec 31;110(3):1059–1064. doi: 10.1073/pnas.1214550110

Fig. 4.

Fig. 4.

Competitive indices (CI) of WT P. aeruginosa (PA14) and the PA0601 mutant (PA0601−) in a murine wound infection model during coculture with S. aureus. Competitive index is defined as the output ratio of P. aeruginosa:S. aureus after 4 d within the chronic wound divided by the input ratio of P. aeruginosa:S. aureus used to initiate the infection at day 1. Each symbol (● or ■) represents values obtained from infection of an individual mouse. P < 0.01 by Mann-Whitney U test for PA14 CI compared with PA0601− CI, n = 12. The number of cfu/g of wound tissue for WT P. aeruginosa (average 5 × 108, SD 3 × 108) and the PA0601 mutant (average 2 × 108, SD 0.8 × 108) in coculture infections after 4 d were not significantly different, P = 0.125 via Mann-Whitney U test n = 12.