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. 2012 Dec 24;110(3):E221–E230. doi: 10.1073/pnas.1208573110

Fig. 6.

Fig. 6.

CDR3 characteristics of TCRα that use TRAV13. (A) Relative frequency of each CDR3 length (in number of amino acids) in CTLA-4WT and CTLA-4KO Tconv and Treg cells. (B) Box and whisker plots of hydrophilicity and PI of CDR3α regions from CTLA-4WT and CTLA-4KO Tconv and Treg cells. Data weighted according to relative expression of each unique CDR3. Horizontal line indicates median value, box covers the interquartile range, bars show variance, gray dots show maximum outliers, and gray crosses display mean. Differences in hydrophilicity and PI between each of the four T-cell groups are all statistically significant (P < 0.0001; Mann–Whitney u test). (C) Correlation plots for hydrophilicity and PI. Each unique CDR3α found more than one time in the cell population indicated was plotted for its specific value and the number of times that it was encountered.