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. 2013 Feb 20;18(6):630–641. doi: 10.1089/ars.2011.4487

FIG. 2.

FIG. 2.

Treatment with FK866 reduces infarct size in vivo after 24 h of reperfusion. Vehicle or FK866 (30 mg/kg) was administered 5 min after ischemia onset and after 12 h of reperfusion. Data are expressed as scattered plots (mean±SEM, n=8 per group). (A) Quantification of area at risk (AAR) per ventricle surface (V). (B) Quantification of infarct size (I) per V: *p<0.05. (C) Representative images of TTC stained middle heart sections of vehicle- or FK866-treated mice. (D) Serum cardiac troponin I (cTnI) levels of vehicle- or 30 mg/kg FK866-treated mice after 1 h, 8 h, and 24 h of reperfusion (n=6–13 per group): **p<0.01. (To see this illustration in color, the reader is referred to the web version of this article at www.liebertonline.com/ars).