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. Author manuscript; available in PMC: 2013 Jan 19.
Published in final edited form as: N Engl J Med. 2011 Jun 5;364(26):2507–2516. doi: 10.1056/NEJMoa1103782

Figure 2. Progression-free Survival.

Figure 2

Panel A shows Kaplan–Meier estimates of progression-free survival in patients in the intention-to-treat population. Patients could be evaluated for progression-free survival if they had undergone randomization at least 9 weeks before clinical cutoff date. The median progression-free survival was 5.3 months for vemurafenib and 1.6 months for dacarbazine. The vertical lines indicate that patients’ data were censored. Panel B shows hazard ratios and 95% confidence intervals (CI) for progression-free survival in prespecified subgroups of patients, according to baseline characteristics. In both panels, data are shown for patients who received no study treatment (48 patients in the dacarbazine group and 2 patients in the vemurafenib group) and for 1 patient who was assigned to the dacarbazine group and who received vemurafenib. NR denotes not reached.