Skip to main content
. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Mol Psychiatry. 2012 Jun 12;18(7):813–823. doi: 10.1038/mp.2012.72

Figure 4.

Figure 4

The lesser-expressing human fatty acid amide hydrolase (FAAH) gene 385A variant is associated with fear-related endophenotypes and traits. (a) Both the right and left amygdala exhibited significant habituation to repeated viewing of threatening faces. (b) Individuals carrying at least one lesser-expressing FAAH 385A variant showed greater amygdala-mediated habituation to threatening stimuli in all three clusters from (a). Given the low occurrence of homozygous AA carriers (n = 3) in this sample, A/A and C/A carriers (n = 31) were combined and compared with C/C homozygotes (n = 50). Data are means±s.e.m. (c, d) AA homozygotes scored significantly lower on a personality endophenotype of Stress Reactivity, measured by the Multidimensional Personality Questionnaire.47 *P<0.05. Data are means±s.e.m.