Table 3.
Description of the sample and the health conditions of the mothers participating in the 2004 Birth Cohort (N), prevalence (P%) and adjusted analyses of the use of medicines during pregnancy considering all medicines and the medicines with unknown fetal risk used. Birth Cohort of Pelotas, RS 2004.
| N | Use of medicines (total) | Use of medicines with unknown fetal risk | |||||
|---|---|---|---|---|---|---|---|
| Characteristic | Adjusted analyses | Adjusted analyses | |||||
| P% | PR (IC 95%) | P value | P% | PR (IC 95%) | P value | ||
| Total of participants | 4,189 | 92.7 | — | — | 52.5 | — | — |
| Age | 0,062 | 0.076 | |||||
| <20 | 796 | 90.8 | 1.00 | 43.6 | 1.00 | ||
| 20 to 29 | 2,085 | 93.1 | 1.58 (1.03–2.43) | 53.2 | 1.09 (0.90–1.32) | ||
| 30 to 39 | 1,170 | 92.9 | 2.01 (1.19–3.38) | 56.9 | 1.31 (1.05–1.64) | ||
| 40 or more | 136 | 94.1 | 2.35 (0.83–6.62) | 55.1 | 1.18 (0.76–1.84) | ||
| Skin color | 0,08 | <0.001 | |||||
| White | 2,555 | 93.8 | 1.31 (0.97–1.78) | 57.7 | 1.36 (1.17–1.58) | ||
| Non-white | 1,586 | 90.9 | 1.00 | 44.1 | 1.00 | ||
| Education in years | 0.026 | <0.001 | |||||
| 0 to 4 | 647 | 87.3 | 1.00 | 32.8 | 1.00 | ||
| 5 to 8 | 1,711 | 91.6 | 1.50 (1.02–2.23) | 47.0 | 1.70 (1.35–2.13) | ||
| 9 to 11 | 1,396 | 95.1 | 1.90 (1.19–3.03) | 62.7 | 2.57 (2.01–3.30) | ||
| 12 or more | 435 | 97.2 | 2.66 (1.22–5.79) | 70.6 | 2.74 (1.95–3.85) | ||
| Marital status | 0.064 | 0.92 | |||||
| With the baby's father | 3,502 | 93.1 | 1.44 (0.98–2.11) | 53.5 | 0.99 (0.81–1.21) | ||
| Without | 687 | 90.5 | 1.00 | 47.0 | 1.00 | ||
| Income per capita | 0.09 | <0.001 | |||||
| 1st quintile | 830 | 88.4 | 1.00 | 38.2 | 1.00 | ||
| 2nd quintile | 834 | 89.2 | 0.83 (0.55–1.25) | 41.7 | 1.03 (0.82–1,30) | ||
| 3rd quintile | 886 | 94.2 | 1,48 (0.93–2.36) | 52.7 | 1.29 (1.03–1.62) | ||
| 4th quintile | 849 | 94.7 | 1.11 (0.68–1.82) | 61.1 | 1.79 (1.41–2.27) | ||
| 5th quintile | 790 | 96.8 | 1.55 (0.81–2.95) | 69.2 | 1.94 (1.47–2.55) | ||
| Parity | 0.025 | 0.52 | |||||
| primipara | 1,658 | 94.8 | 2.45 (1.34–4.46) | 55.9 | 1.12 (0.81–1.56) | ||
| 1 or 2 | 1,086 | 93.0 | 1.65 (0.96–2.82) | 54.8 | 1.06 (0.78–1.45) | ||
| 3 or 4 | 1,026 | 91.6 | 1.36 (0.83–2.23) | 48.6 | 0.95 (0.70–1.27) | ||
| 5 or more | 419 | 86.2 | 1.00 | 42.2 | 1.00 | ||
| Prenatal consultation | 0.004 | 0.001 | |||||
| <6 | 689 | 86.6 | 1.00 | 36.0 | 1.00 | ||
| 6 or more | 3,250 | 94.9 | 1.65 (1.18–2.32) | 56.8 | 1.39 (1.14–1.70) | ||
| Start of prenatal care | 0.70 | 0.32 | |||||
| Before the 20th week | 3,765 | 94.0 | 1.10 (0.68–1.80) | 54.8 | 1.18 (0.85–1.64) | ||
| After the 20th week | 283 | 84.8 | 1.00 | 31.4 | 1.00 | ||
| Hospitalization | |||||||
| No | 3,722 | 91.9 | 1.00 | 0.002 | 50.9 | 1.00 | 0.05 |
| Yes | 467 | 98.9 | 6.50 (1.99–21.21) | 64.7 | 1.28 (1.00–1.62) | ||
| High Blood Pressure | 0.012 | 0.87 | |||||
| No | 3,189 | 92.3 | 1.00 | 52.6 | 1.00 | ||
| Yes | 992 | 94.0 | 1.60 (1.11–2.31) | 52.3 | 0.90 (0.59–1.37) | ||
| Diabetes | 0.76 | 0.63 | |||||
| No | 4,062 | 92.6 | 1.00 | 52.4 | 1.00 | ||
| Yes | 124 | 96.0 | 0.86 (0.32–2.30) | 56.4 | 0.90 (0.59–1.37) | ||
| Depression | 0.034 | <0.001 | |||||
| No | 3,138 | 92.1 | 1.00 | 51.0 | 1.00 | ||
| Yes | 1049 | 94.3 | 1.49 (1.03–2.16) | 56.9 | 1.38 (1.16–1.64) | ||
| Anemia | <0.001 | <0.001 | |||||
| No | 1,402 | 83.0 | 1.00 | 42.7 | 1.00 | ||
| Yes | 2756 | 97.8 | 10.79 (7.68–15.16) | 57.7 | 1.53 (1.31–1.78) | ||
| Threat of abortion | 0.15 | <0.001 | |||||
| No | 3,736 | 92.2 | 1.00 | 50.0 | 1.00 | ||
| Yes | 449 | 96.4 | 1.55 (0.85–2.83) | 73.0 | 2.40 (1.84–3.11) | ||
| Threat of premature labor | <0.001 | <0.001 | |||||
| Não | 3,416 | 91.7 | 1.00 | 48.0 | 1.00 | ||
| Sim | 771 | 97.0 | 2.72 (1.57–4.73) | 72.5 | 2.65 (2.15–3.27) | ||
| Urinary Infection | <0.001 | 0.012 | |||||
| Não | 2,623 | 89,8 | 1.00 | 52.5 | 1.00 | ||
| Sim | 1,552 | 97.7 | 5.53 (3.58–8.54) | 52.5 | 0.82 (0.71–0.96) | ||
*Chi square test; **1st quintile relates to the most deprived quintile ***PR: prevalence ratio.