Figure 2.

Effect of berry extracts and polyphenols on proliferation of ICI-resistant (LCC9 and ZR75-1R) cell lines. Cell proliferation results from 6 d treatment of various cell lines with respective berry extract or polyphenol. Yellow (light) bars represent extract/polyphenol only and blue (dark) bars represent extract/polyphenol + 1 nM ICI. Each extract or polyphenol used for treatment was diluted 1000-fold from stock concentration. Vehicle treatment contained 0.01% EtOH and 0.1% DMSO. All treatments were normalized to the appropriate vehicle treatment. Data represented is mean ± standard error of three individual experiments performed in triplicate for each treatment. The means were tested for difference using a t-test and a P ≤ 0.05 considered significant.