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. Author manuscript; available in PMC: 2013 Jan 20.
Published in final edited form as: J Neurochem. 2012 Mar 13;121(2):302–313. doi: 10.1111/j.1471-4159.2012.07678.x

Fig. 5.

Fig. 5

Cocaine significantly decreases Neurogranin expression levels. Western analyses of protein levels of (a) D2, (b) D3 and (c) Ng were assessed after 14 days cocaine administration. No significant changes in D2 or D3 were observed among groups. (c, left panel) Ng mRNA and (c, right panel and d) protein levels were significantly decreased in cocaine-treated mice compared with control. (e) Neurogranin (green) immunofluorescent labeling of hippocampal tissue from representative control and cocaine-treated mice. Nuclei are labeled with DAPI (blue). (e) Magnification 400×. D2, deiodinase 2 enzyme; D3, deiodinase 3 enzyme; Ng, neurogranin; Hypo, hypothyroid. Data were analyzed by one-way ANOVA with Tukey’s multiple comparison post hoc test. n ≥ 6 mice per group. *p < 0.05.