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Treatment groups
| Group | Treatment |
|---|---|
| 1 | Euthyroid |
| 2 | Cocaine no WD |
| 3 | Cocaine + WD + challenge |
| 4 | Hypo |
| 5 | SCH |
| 6 | Hypo + cocaine + WD + challenge |
| 7 | SCH + cocaine + WD + challenge |
Euthyroid, control; Hypo, Hypothyroid, PTU-fed; Cocaine, 14 days, 15 mg/kg; WD, 48 h withdrawal; challenge, 15 mg/kg challenge dose cocaine; SCH, subclinical hypothyroid (0.075% dose PTU).
N = 6–10 mice per group.
