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. Author manuscript; available in PMC: 2013 Nov 27.
Published in final edited form as: Life Sci. 2012 Aug 22;91(21-22):1070–1076. doi: 10.1016/j.lfs.2012.08.020

Figure 2. Topical nicotine and α-bungarotoxin (Bung) treatment increases barrier permeability beyond the stratum corneum.

Figure 2

Lucifer Yellow was retained in the stratum corneum in vehicle (A) treated mouse skin. Lucifer Yellow penetrated into the basal layers of the epidermis and dermis in nicotine (B) and Bung (C) treated mouse skin. Lucifer Yellow was retained in the epidermis in combined nicotine + Bung treated mouse skin (D). Scale bar= 200μm