. Author manuscript; available in PMC: 2013 Apr 1.

Published in final edited form as: Biochem J. 2012 Apr 1;443(1):259–266. doi: 10.1042/BJ20111994

Table 1. Localization of TFPI to caveolae does not affect its fXa inhibitory activity.

The fXa inhibitory assay was performed on CHO-TF, CHO-TF/TFPI-TM, and CHO-TF/TFPI-GPI cells in suspension at equivalent concentrations (300 µg/mL total cellular protein). Numbers represent the mean ± SD.

	Free Factor Xa (nM)
Cell Line	Initial	Final
CHO-TF	0.077 ± 0.041	0.091 ± 0.035

CHO-TF/TFPI-TM	0.079 ± 0.019	0.025 ± 0.020^*

CHO-TF/TFPI-GPI	0.083 ± 0.016	0.019 ± 0.016^†

- p < 0.05 vs. CHO-TF cells;

^†

- p < 0.01 vs. CHO-TF cells; n = 6.