FIG. 3.
HUCBC infusion reduces β-amyloid pathology in PSAPP mice. (a) Mouse brain sections from both 6- and 10-month treated PSAPP mice with HUCBCs were stained with anti-Aβ17–24 antibody (4G8: brown) at 12 and 16 months of age. (b) Percentage of Aβ 4G8 antibody immunoreactive plaques from hippocampus [mean±SE; n=10 (5♀/5♂ per group)] was quantified by image analysis. A t-test for independent samples revealed significances between groups (**P<0.01). SE, standard error. Color images available online at www.liebertpub.com/scd