FIG. 4.

HUCBC infusion reduces microgliosis in PSAPP mice. (a) Mouse brain sections from both 6- and 10-month treated PSAPP mice with HUCBCs were stained with anti-CD45 antibody (brown) at 12 and 16 months of age. (b) Percentage of CD45 positive microglial cells from entorhinal cortex [mean±SE; n=10 (5♀/5♂ per group)] was quantified by image analysis. A t-test for independent samples revealed significances between groups (**P<0.01; ***P<0.001). Color images available online at www.liebertpub.com/scd