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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: J Am Acad Child Adolesc Psychiatry. 2013 Jan;52(1):94–103.e3. doi: 10.1016/j.jaac.2012.10.013

Figure 1.

Figure 1

Regional gray matter volumes (GMV) significantly associated with Total Psychopathy Checklist– Youth Version (PCL-YV) scores, controlling for brain volume (BV), age at scan, and substance dependence. Note: These regions are significant in the whole brain at p<.05, uncorrected for multiple comparisons, with an extent threshold of 1643 voxels, yielding a corrected threshold of p<.05, accounting for spatial correlations between GMVs in neighboring voxels. Coordinates are in Montreal Neurological Institute (MNI) space. The color bar represents t-values. GMV increases are in yellow/orange/red and decreases are in green/blue. Negatively associated clusters can be found in the orbitofrontal cortex (OFC), extending into parahippocampal cortex and the temporal poles, and in the posterior cingulated cortex (PCC). There is a positively associated cluster in the prefrontal cortex.