Table 1.

Classification of hemophagocytic syndrome

Type of hemophagocytic syndrome	Subtype
Primary or genetic hemophagocytic syndrome	Familial hemophagocytic lymphohistiocytosis
	Immune deficiency syndromes (i.e., Chediak-Higashi syndrome, Griscelli syndrome, X-linked lymphoproliferative syndrome)
Secondary or reactive hemophagocytic syndrome	Infections (i.e., viral, bacterial, parasitic)
	Malignancies
	Auto-immune and auto-inflammatory diseases