Table 1.
Description | Symbol | Value | References |
---|---|---|---|
Total number of patients |
Np |
600 |
|
Total number of HCWs |
Nh |
150 |
|
(Patients: HCWs = 3:1) |
|
|
[19] |
Probability that a person is colonized by MRSA at admission |
λc |
0.04 |
[24] |
Probability that a person is infected with MRSA at admission |
λi |
0.001 |
[25] |
Average length of stay of an uncolonized patient (days) |
1/γu |
5 |
[24] |
Average length of stay of a colonized patient (days) |
1/κ |
7 |
[20] |
Probability of becoming infectious |
m1 |
0.3 |
[23] |
Probability of decolonization |
m2 |
0.01 |
estimated∗ |
Rate of progression from colonization to infection |
ϕ |
m1κ |
|
Rate of decolonization |
ω |
m2κ |
|
Discharge rate of colonized patients |
γc |
(1 − m1 − m2)κ |
|
(including death from other causes) |
|
|
|
Average duration of treatment of an infected patient (days) |
1/τ |
14 |
[1] |
Probability of a successful treatment |
ρ |
0.6 |
[26] |
Death rate of an infected patient |
γi |
(1−ρ)τ |
|
(from both disease-related and other causes) |
|
|
|
Total number of contacts that a patient requires per day |
a |
8 |
[19] |
Probability of colonization after a contact with a HCW |
bp |
0.01 |
[27] |
Probability of contamination after a contact with a colonized patient |
bhc |
0.15 |
[27] |
Probability of contamination after a contact with an infected patient |
bhi |
0.30 |
estimated |
Average duration of contamination (days) | 1/μ | 1/24 | [27] |
*Note that the probability of decolonization of a colonized patient is estimated by the normal time require for nasal MRSA to revert to the usual MSSA (methicillin-sensitive Staphylococcus aureus) which is approximately 30 days [28]. Hence, we here estimate the probability of decolonization by probability that a patient stays longer than thirty days [29].