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. 2012 Jun 27;9:25. doi: 10.1186/1742-4682-9-25

Table 1.

List of parameters for MRSA transmission in hospital settings

Description Symbol Value References
Total number of patients
Np
600
 
Total number of HCWs
Nh
150
 
(Patients: HCWs = 3:1)
 
 
[19]
Probability that a person is colonized by MRSA at admission
λc
0.04
[24]
Probability that a person is infected with MRSA at admission
λi
0.001
[25]
Average length of stay of an uncolonized patient (days)
1/γu
5
[24]
Average length of stay of a colonized patient (days)
1/κ
7
[20]
Probability of becoming infectious
m1
0.3
[23]
Probability of decolonization
m2
0.01
estimated
Rate of progression from colonization to infection
ϕ
m1κ
 
Rate of decolonization
ω
m2κ
 
Discharge rate of colonized patients
γc
(1 − m1 m2)κ
 
(including death from other causes)
 
 
 
Average duration of treatment of an infected patient (days)
1/τ
14
[1]
Probability of a successful treatment
ρ
0.6
[26]
Death rate of an infected patient
γi
(1−ρ)τ
 
(from both disease-related and other causes)
 
 
 
Total number of contacts that a patient requires per day
a
8
[19]
Probability of colonization after a contact with a HCW
bp
0.01
[27]
Probability of contamination after a contact with a colonized patient
bhc
0.15
[27]
Probability of contamination after a contact with an infected patient
bhi
0.30
estimated
Average duration of contamination (days) 1/μ 1/24 [27]

*Note that the probability of decolonization of a colonized patient is estimated by the normal time require for nasal MRSA to revert to the usual MSSA (methicillin-sensitive Staphylococcus aureus) which is approximately 30 days [28]. Hence, we here estimate the probability of decolonization by probability that a patient stays longer than thirty days [29].