Table 2.
Top 20 term associations in category "overlap but not identical" that were identified by CroGO.
MF Name | BP Name | Evidence |
polynucleotide adenylyltransferase activity | ncRNA polyadenylation | NEW |
TFIIF-class binding TF activity | regulation of transcription-coupled nucleotide-excision repair | REF [37] |
TFIIF-class binding TF activity | positive regulation of transcription elongation from Pol I promoter | REF [38] |
TFIIF-class binding TF activity | regulation of transcription elongation from Pol I promoter | REF [38] |
TFIIF-class binding TF activity | positive regulation of histone H3-K36 trimethylation | NEW |
TFIIF-class binding TF activity | regulation of histone H3-K36 trimethylation | NEW |
TFIIF-class binding TF activity | positive regulation of histone H3-K36 methylation | NEW |
TFIIF-class binding TF activity | regulation of nucleotide-excision repair | REF [39] |
TFIIF-class binding TF activity | regulation of histone H2B ubiquitination | REF [40] |
TFIIF-class binding TF activity | positive regulation of phosphorylation of Pol II C-terminal domain serine 2 residues | NEW |
TFIIF-class binding TF activity | regulation of phosphorylation of Pol II C-terminal domain serine 2 residues | NEW |
TFIIF-class binding TF activity | regulation of histone H2B conserved C-terminal lysine ubiquitination | NEW |
IMP dehydrogenase activity | GTP biosynthetic process | REF [41] |
hydrogen ion transporting ATP synthase activity, rotational mechanism | ATP biosynthetic process | LEXICAL |
RNA-directed RNA polymerase activity | tRNA transcription from Pol III promoter | LEXICAL |
RNA-directed RNA polymerase activity | tRNA transcription | NEW |
protein prenyltransferase activity | protein geranylgeranylation | REF [42] |
second spliceosomal transesterification activity | generation of catalytic spliceosome for second transesterification step | NEW |
oxoglutarate dehydrogenase activity | 2-oxoglutarate metabolic process | LEXICAL |
peptide alpha-N-acetyltransferase activity | N-terminal protein amino acid acetylation | REF [43] |
Top 20 term associations in category "overlap but not identical" that were identified by CroGO. In the list, 8 term associations are supported by the existing biological studies, 3 are supported by the lexical matching on term definition, and the rest 7 are new conceptual connections that cannot be found in any literature. Only 3 of the term associations can be identified by the VSM or ASR based measures.