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. 2013 Jan 21;14(Suppl 2):S13. doi: 10.1186/1471-2105-14-S2-S13

Table 1.

Results of MHC-PPM in class I predictions in Peters dataset [22].

Allele # Peptides ANN ARB SMM MHC-PPM
9 10
9-mers + 10-mers HLA-A*0201 3089 1316 - 0.919 0.939 0.931
HLA-A*0202 1447 1056 - 0.851 0.879 0.871
HLA-A*0203 1443 1055 - 0.838 0.878 0.882
HLA-A*0301 2094 1082 - 0.883 0.915 0.911
HLA-A*0206 1437 1054 - 0.849 0.890 0.885
HLA-A*1101 1985 1093 - 0.897 0.932 0.937
HLA-A*2402 197 78 - 0.722 0.809 0.833
HLA-A*3101 1869 1057 - 0.881 0.903 0.878
HLA-A*3301 1140 1055 - 0.866 0.888 0.863
HLA-A*6801 1141 1055 - 0.827 0.874 0.864
HLA-B*0702 1262 205 - 0.925 0.952 0.954
HLA-B*3501 736 177 - 0.833 0.886 0.866
HLA-B*5101 244 177 - 0.782 0.875 0.886
HLA-B*5301 254 177 - 0.758 0.854 0.847

9-mers HLA-A*0101 1157 - 0.982 0.964 0.980 0.963
HLA-A*2601 672 - 0.956 0.907 0.931 0.901
HLA-A*2902 160 - 0.935 0.755 0.911 0.907
HLA-A*6802 1434 - 0.899 0.865 0.898 0.867
HLA-B*0801 708 - 0.955 0.936 0.943 0.926
HLA-B*1501 978 - 0.941 0.900 0.952 0.922
HLA-B*1801 118 - 0.838 0.573 0.853 0.906
HLA-B*2705 969 - 0.938 0.915 0.940 0.938
HLA-B*4002 118 - 0.754 0.541 0.842 0.891
HLA-B*4402 119 - 0.778 0.533 0.740 0.891
HLA-B*4403 119 - 0.763 0.461 0.770 0.847
HLA-B*5401 255 - 0.903 0.847 0.921 0.883
HLA-B*5701 59 - 0.826 0.428 0.871 0.929
HLA-B*5801 988 - 0.961 0.889 0.964 0.944

Average (All) 0.888 0.798 0.893 0.897
Average (9mers) 0.888 0.751 0.894 0.908
Weighted Avg 0.932 0.872 0.910 0.901

The best-performing method for each allele is underlined. The given AUC values for ARB and SMM are the weighted averages of the AUC values for 9-mers and 10-mers based on the given peptide counts for a specific allele. The alleles in the bottom part of the table were only trained & tested in 9-mers and are directly comparable.