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. 2013 Jan 1;8(1):28–33. doi: 10.4161/epi.23366

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Copyright © 2013 Landes Bioscience

This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.

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graphic file with name epi-8-28-g3.jpg — Figure 3. Candidate genes for premature aging phenotypes. (A) Absolute DNA methylation levels of CpG sites in the promoter region of LOC149837 of non-mutant patients (AG) and healthy donors (LCL). The distance to the transcription start site (TSS) is indicated. (B) DNA methylation levels (low: green; high: red) of LOC149837 promoter CpG sites in all analyzed premature aging patients (AG) and healthy donors (LCL). The cluster was calculated using Manhattan distances. (C) Absolute DNA methylation level of CpG sites in the promoter region of POLD3 of non-mutant patients (AG) and healthy donors (LCL). The distance to the transcription start site (TSS) is indicated.