Table 2.

User reported clinical effects of synthetic cathinones [17, 25, 28, 30, 62]

Cardiovascular	Palpitations, shortness of breath, chest pain
ENT	Dry mouth, epistaxis, nasal pain, “nose burns”, oropharyngeal pain, tinnitus
Gastrointestinal	Abdominal pain, anorexia, nausea, vomiting
Genitourinary	Anorgasmia, erectile dysfunction, increased libido
Musculoskeletal	Arthralgias, extremity changes—coldness, discoloration, numbness, tingling, muscular tension and cramping
Neurologic	Aggressiveness, bruxism, dizziness, headache, lightheadness, memory loss, tremor, seizures
Ophthalmologic	Blurred vision, mydriasis, nystagmus
Pulmonary	Shortness of breath
Psychological	Anger, anxiety, auditory and visual hallucinations, depression, dysphoria, empathy, euphoria, fatigue, formication, increased energy, increased and decreased concentration, loquaciousness, panic, paranoia, perceptual distortions, restlessness
Other	Body odor “mephedrone stink”, diaphoresis, fever, insomnia, nightmares, skin rash

These are self-reported symptoms by users of synthetic cathinones. It is possible that these effects are not all related to cathinone use as many users take these substances simultaneously with other drugs and ethanol. Additionally due to lack of reliability and consistency of products, users may not be aware of what drug they have actually taken. Please see text for more information