Table 1.
Amlodipine ingestions with reported blood levels and outcome
Age and gender | Peak serum amlodipine level | Reported dose ingested | Outcome | |
---|---|---|---|---|
11-month-old male | 1,300 ng/ml | 10 to 45 mg 0.9 to 4.1 mg/kg | Fatality, hypotension, tachycardia, refractory shock | Present case |
63-year-old female | 185 ng/ml | 70 mg | Fatality, hypotension, bradycardia, ventricular dysrhythmias, refractory shock after 24 h | Koch et al. [8] |
50-year-old male | 2,300 ng/ml (postmortem) | Unknown | Fatality, no clinical details available | Johansen et al. [11] |
15-year-old female | 2,700 ng/ml (postmortem) | 140 mg | Fatality, hypotension, tachycardia | Cosbey et al. [6] |
44-year-old male | 2,400 ng/ml (postmortem heart blood) | Unknown | Fatality, no clinical details available | Sklerov [10] |
66-year-old female | 870 ng/ml (postmortem peripheral blood) | Unknown | Fatality, no clinical details available | Sklerov [10] |
950 ng/ml (postmortem heart blood) | ||||
Not listed | 940 ng/ml | Unknown | Fatality, also found velafaxine citalopram | Linnet et al. [9] |
76-year-old male | 67 ng/ml | 100 mg | Survived, hypotention, acute renal failure, pulmonary edema | Adams et al. [2] |
43-year-old male | 143 ng/ml | 350 mg | Survived, tachycardia | Poggenborg et al. [13] |
42-year-old male | 393 ng/ml | 1,000 mg | Survived, hypotension, reduced ventricular ejection fraction, pulmonary edema | Vogt et al. [14] |
42-year-old female | 88 ng/ml | 50–100 mg | Survived, hypotension, tachycardia, pulmonary edema | Staneck et al. [15] |
22-year-old female | 150 ng/ml | 425 mg | Survived, hypotension, tachycardia, third degree AV block, acute renal failure | Ezidiegwu et al. [16] |
37-year-old male | 130 ng/ml | 6.7 mg/kg | Survived, hypotension, bradycardia, third degree AV block, also ingested atenaolol and alprazolam | Yuan et al. [23] |