Figure 7.

Average trajectories (±standard errors) of four physiological variables for carriers (“e4”) and non-carriers (“not e4”) of the APOE e4 allele in the Framingham Heart Study (original cohort, pooled data from exams 1–28). (A) Body mass index; (B) diastolic blood pressure; (C) cholesterol; (D) ventricular rate. Symbols above the curves correspond to p-values for testing the null hypotheses on equality of means in respective age groups: no symbol: p ≥ 0.05; ^*: 0.01 ≤ p < 0.05; ^#: 0.001 ≤ p < 0.01; ^!: 0.0001 ≤ p < 0.001; ^!!: p < 0.0001.