Table 3.

Effects of polygenic score on total and cause-specific mortality in the Cox model.

Cause	Events #	Cens. #	Beta	SE	p-value	HR (95% C.I.)
Total	1267	204	−0.057	0.007	2.7E-18	0.94 (0.93; 0.96)
CVD	368	1103	−0.047	0.012	0.0001	0.95 (0.93; 0.98)
Cancer	243	1228	−0.030	0.015	0.041	0.97 (0.94; 0.99)
Other	656	815	−0.071	0.009	1.9E-15	0.93 (0.92; 0.95)

Notes: “Cause” denotes the cause of death (Total—all causes, CVD, cancer, and Other—all other causes or unknown cause); “Events #” shows the number of deaths from specific cause; “Cens. #” indicates the number of censored cases; “Beta” shows the estimate of the regression coefficient for the polygenic score variable in the Cox model; “SE” is a standard error for Beta; “p-value” characterizes the significance of the estimate; “HR” shows the estimate of hazard ratio per one SNP (pro-survival allele), 95% confidence intervals are shown in parentheses.