Table 3.
Warfarin treatment by HAS-BLED and CHADS2 score
60–69 years | 70–79 years | 80+ years (reference group) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
CHADS2 | Age group | Patients n | Patients treated with warfarin (%) | χ2 Value* | p Value* | Patients n | Patients treated with warfarin (%) | χ2 Value† | p Value† | Patients n | Patients treated with warfarin (%) |
0 | HAS-BLED > CHADS2 | 4265 | 49 | – | – | 3998 | 51 | – | – | 0 | – |
HAS-BLED≤CHADS2 | 1978 | 49 | – | – | 0 | – | – | – | 0 | – | |
1 | HAS-BLED>CHADS2 | 2880 | 56 | 692 | <0.0001 | 5556 | 52 | 697 | <0.0001 | 3801 | 25 |
HAS-BLED≤CHADS2 | 3821 | 60 | 814 | <0.0001 | 4309 | 56 | 640 | <0.0001 | 4492 | 29 | |
2 | HAS-BLED>CHADS2 | 512 | 55 | 130 | <0.0001 | 2296 | 52 | 266 | <0.0001 | 3286 | 30 |
HAS-BLED≤CHADS2 | 2137 | 65 | 772 | <0.0001 | 6997 | 58 | 1022 | <0.0001 | 10596 | 33 | |
3 | HAS-BLED>CHADS2 | 128 | 52 | 31 | <0.0001 | 419 | 53 | 71 | <0.0001 | 526 | 26 |
HAS-BLED≤CHADS2 | 965 | 69 | 419 | <0.0001 | 4157 | 58 | 554 | <0.0001 | 6524 | 34 | |
4+ | HAS-BLED>CHADS2 | 7 | 57 | 3 | 0.0762 | 62 | 53 | 13 | 0.0004 | 111 | 26 |
HAS-BLED≤CHADS2 | 361 | 66 | 129 | <0.0001 | 2556 | 57 | 286 | <0.0001 | 4641 | 36 |
*χ2 tests comparing the proportion of patients treated with warfarin in the 60–69 years age group compared with the 80+ years age group.
†χ2 tests comparing the proportion of patients treated with warfarin in the 70–79 years age group compared with the 80+ years age group.