Table 2.
Antiphospholipid antibodies in mothers before and during pregnancy
| At diagnosis (n=133) | 1st Trimester (n=87) | 2nd Trimester (n=46) | 3rd Trimester (n=46) | |
|---|---|---|---|---|
| Lupus anticoagulant | 33 (25%) | 16 (18%) | 6 (13%) | 6 (13%) |
| Anticardiolipin IgG | 66 (50%) | 34 (39%) | 23 (50%) | 11 (24%) |
| Anticardiolipin IgG (UGPL) | 48±105* | 30±54 | 24±43 | 31±97 |
| Anticardiolipin IgM | 16 (12%) | 9 (10%) | 1 (2%) | 2 (4%) |
| Anticardiolipin IgM (UMPL) | 7±12 | 5±5 | 6±8 | 6±12 |
| Anti-β2GPI IgG | 32 (25%) | 22 (25%) | 10 (22%) | 5 (11%) |
| Anti-β2GPI IgG (UGPL) | 8±18 | 7±11 | 6±7 | 11±28 |
| Anti-β2GPI IgM | 25 (19%) | 19 (22%) | 10 (22%) | 4 (10%) |
| Anti-β2GPI IgM (UMPL) | 4±8 | 7±11 | 6±7 | 3±4 |
Values are means with SD. Anti-β2GPI, anti-β2 glycoprotein-I antibodies.
*
p<0.05 from baseline at diagnosis to 1st, 2nd and 3rd trimester of pregnancy.
anti-β2GPI, anti-β2 glycoprotein-I; IgG, immunoglobulin G.