Table 2.
Modification | Modifier | Histone | Role in DNA repair | Reference |
---|---|---|---|---|
K4me3 | SET1 | H3 | Stimulates V(D) J recombination via recombination activating gene (RAG) complex | Wang et al. (2009), Stanlie et al. (2010) |
K9me3 | Suv3-9H1/ Suv3-9H2 | H3 | Interacts with HP1β, phosphorylates damage-induced HP1β, and activates TIP60 | Ayoub et al. (2008), Sun et al. (2009) |
K36me2 | Metnase/SETMAR | H3 | Accumulates NBS1 and Ku to stimulate NHEJ | De Haro et al. (2010), Beck et al. (2011) |
K79me3 | DOT1 | H3 | Recruits RAD9 in budding yeast | Bostelman et al. (2007) |
K20me2 | Suv4-20H1/Suv4-20H2;MMSET | H4 | Recruits DDR and repair proteins | Sanders et al. (2004), Schotta et al. (2004), Pei et al. (2011) |