Table 4.

Ubiquitination.

Modification	Modifier	Histone	Role in DNA repair	Reference
K119ub/K119ub2, K119poly-ub	RNF8, RNF168	H2A	Accumulates BRAC1 and 53BP1 for DNA repair	Ikura et al. (2007)
K119ub/K119ub2, K119poly-ub	RNF8, RNF168, TIP60–UBC13	H2AX	Recruits DDR proteins to the repair lesion	Mailand et al. (2007), Doil et al. (2009), Stewart et al. (2009)
K120ub	RNF20–RNF40	H2B	Recruits XRCC4 and Ku for NHEJ and BRCA1 and RAD51 FOR HR	Moyal et al. (2011), Nakamura et al. (2011)
K91ub	BBAP	H4	Induces H4K20me modification and recruits 53BP1 to promote NHEJ	Yan et al. (2009)