Table 2.
ALVIN | FSL FIRST | FreeSurfer | ||
---|---|---|---|---|
Accuracy | Young Adults (ICC) | 0.992 | 0.902 | 0.994 |
Alzheimer’s Disease (ICC) | 0.973 | N/Aa | 0.998 | |
Infants (ICC) | 0.953 | 0.901 | 0.959 | |
Reproducibility | Test-retest, same scanner and pulse sequence (ICC) | 0.999 | 0.996 | 0.998 |
Different scanner and pulse sequence (ICC) | 0.994 | 0.981 | 0.997 | |
Reproducibility T1/T2 (ICC) | 0.982 | 0.925 | N/Aa | |
Sensitivity | Paired t-test between baseline and follow-up scan (Z score) | 6.55, p<0.001 | N/Aa | 5.71, p<0.001 |
Correlation of volume change and interscan interval (R value) | 0.52, p<0.001 | N/Aa | 0.60, p<0.001 | |
Speed | Time to process one subject (minutes) | 8 | 7 | 420 |
Algorithms with a greater than 50% failure rate were not included in the ICC analysis