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. Author manuscript; available in PMC: 2013 Jan 22.
Published in final edited form as: Neuroimage. 2011 Jul 30;58(4):1051–1059. doi: 10.1016/j.neuroimage.2011.06.080

Table 2.

Accuracy, reproducibility, sensitivity and speed of the 3 algorithms in segmenting the lateral ventricles.

ALVIN FSL FIRST FreeSurfer
Accuracy Young Adults (ICC) 0.992 0.902 0.994
Alzheimer’s Disease (ICC) 0.973 N/Aa 0.998
Infants (ICC) 0.953 0.901 0.959
Reproducibility Test-retest, same scanner and pulse sequence (ICC) 0.999 0.996 0.998
Different scanner and pulse sequence (ICC) 0.994 0.981 0.997
Reproducibility T1/T2 (ICC) 0.982 0.925 N/Aa
Sensitivity Paired t-test between baseline and follow-up scan (Z score) 6.55, p<0.001 N/Aa 5.71, p<0.001
Correlation of volume change and interscan interval (R value) 0.52, p<0.001 N/Aa 0.60, p<0.001
Speed Time to process one subject (minutes) 8 7 420
a)

Algorithms with a greater than 50% failure rate were not included in the ICC analysis