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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: Best Pract Res Clin Gastroenterol. 2012 Feb;26(1):3–16. doi: 10.1016/j.bpg.2012.01.014

Table 1. Comparison of Different ALF Etiology Groups.

Clinical and demographic features of acute liver failure according to etiologic groups. Acetaminophen-related ALF is considered hyperacute and demonstrates the very high aminotransferase and low bilirubin levels, compared to drug-induced liver injury which is more indolent.

APAP
n=787
Drug
n=202
Indeterminate
n=219
HepA/HepB
n=37/123
All Others
N=328
Age (median) 37 47 38 48/43 45
Sex (% F) 76 66 60 46/45 73
Jaundice
(Days)
(median)
0 8 8 3/5 4
Coma ≥3 (%) 53 37 50 51/55 43
ALT (median) 3846 685 849 2124/1702 677
Bili (median) 4.4 19.8 22.0 12.5/19.1 14.6
Tx (%) 9 40 45 32/41 30
Spontaneous
Survival (%)
67 31 27 54/24 38
Overall
Survival (%)
75 68 69 84/61 65