Table 2. Clinicopathological features in relation to Gli1 nuclear immunoreactivity.
| Case No. | Gli1 nuclear immunoreactivity |
P | ||
|---|---|---|---|---|
| Low | High | |||
| Age (year) | ||||
| ≤35 | 12 | 6 | 6 | <0.001 |
| 36–59 | 180 | 37 | 143 | |
| ≥60 | 92 | 5 | 87 | |
| T-classification | ||||
| T1 | 148 | 23 | 125 | 0.094 |
| T2 | 105 | 15 | 90 | |
| T3 | 29 | 9 | 20 | |
| T4 | 2 | 1 | 1 | |
| N-classification | ||||
| N0 | 147 | 23 | 124 | 0.080 |
| N1 | 107 | 15 | 92 | |
| N2 | 25 | 8 | 17 | |
| N3 | 5 | 2 | 3 | |
| Clinical stage | ||||
| I | 129 | 26 | 103 | 0.362 |
| II | 113 | 15 | 98 | |
| III | 42 | 7 | 35 | |
| ER presence | ||||
| Negative | 115 | 21 | 94 | 0.616 |
| Positive | 169 | 27 | 142 | |
| PR presence | ||||
| Negative | 138 | 25 | 113 | 0.597 |
| Positive | 146 | 23 | 123 | |
| HER-2 presence | ||||
| Negative | 88 | 18 | 70 | 0.019 |
| Positive | 196 | 30 | 166 | |
Low, IRS=0-6; High, IRS=7-12; ER, estrogen receptor; PR, progesterone receptor; HER-2, human epidermal growth factor receptor 2