Table 3. Hematological and non-hematological adverse events (NCI-CTCAE version 2.0).
| Type of adverse event (n=75) | All grades |
Grade III, IV |
|||
|---|---|---|---|---|---|
| n | % | n | % | ||
| Hematologic toxicity | |||||
| Neutropenia | 74 | 98.6 | 31 | 41.3 | |
| Febrile neutropenia | 7 | 9.3 | 7 | 9.3 | |
| Thrombocytopenia | 11 | 14.6 | 0 | 0 | |
| Anemia | 42 | 56.0 | 2 | 2.7 | |
| Nonhematologic toxicity | |||||
| Fatigue/malaise | 50 | 66.7 | 0 | 0 | |
| Nausea/anorexia | 68 | 90.7 | 8 | 10.7 | |
| Vomiting | 46 | 61.3 | 4 | 5.3 | |
| Diarrhea | 12 | 1.3 | 0 | 0 | |
| Alopecia | 69 | 92.0 | 0 | 0 | |
| Stomatitis | 16 | 21.3 | 0 | 0 | |
| Neurosensory toxicity | 36 | 48.0 | 2 | 2.6 | |
| AST/ALT | 8 | 10.6 | 0 | 0 | |
| Bilirubin elevation | 5 | 6.7 | 0 | 0 | |
| Creatinine | 2 | 2.6 | 0 | 0 | |
NCI-CTCAE, National Cancer Institute-Common Terminology Criteria for Adverse Events