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Example of the similarity between aged and DEARE mice. Left: H & E section of a 15 Gy day 192 sample. The villi are short and wide with fewer cells in the lamina propria. Mid: A control 5 month old mouse with longer villi and normal looking lamina propria. Right: A 32 month old mouse. The broad spade-like villi result in a reduced absorptive surface area and a less flexible structure, both of which contribute to a failure to thrive.
