Table 6.
Prognostic factors associated with the odds of experiencing an acute or a late toxicity, adjusted for age, grade, treatment length, stage and histologic type
Odds ratio and 95% confidence interval associated with 5 Gy of: | Acute toxicity | Late toxicity | ||||
---|---|---|---|---|---|---|
N | Odds ratio and 95% confidence interval | p-value | N | Odds ratio and 95% confidence interval | p-value | |
Rectal dose (average) | 95 | 0.98 (0.95, 1.01) | 0.31 | 84 | 1.00 (0.96, 1.05) | 0.93 |
Rectal dose (max) | 96 | 1.00 (0.98, 1.02) | 0.83 | 85 | 1.02 (0.99, 1.05) | 0.20 |
Equivalent dose for tumor effects (Gy) Bladder | 89 | 0.99 (0.70, 1.36) | 0.95 | 81 | 0.90 (0.55, 1.39) | 0.63 |
Equivalent dose (late effects no DMF) Bladder | 88 | 1.00 (0.80, 1.22) | 0.98 | 80 | 0.96 (0.70, 1.25) | 0.76 |
Equivalent dose for tumor effects(Gy) Surface | 91 | 1.26 (0.72, 2.31) | 0.43 | 81 | 1.61 (0.84, 3.61) | 0.18 |
Equivalent dose (late effects no DMF) Surface | 91 | 1.13 (0.85, 1.54) | 0.40 | 81 | 1.05 (0.77, 1.46) | 0.74 |
Equivalent dose for tumor effects (Gy) 0.5 mm | 98 | 0.28 (0.01, 1.84) | 0.45 | 87 | 0.97 (0.03, 2.82) | 0.97 |
Equivalent dose (late effects no DMF) 0.5 mm | 98 | 0.52 (0.14, 1.28) | 0.29 | 87 | 1.02 (0.29, 1.73) | 0.97 |
DMF – dose modifying factor