Table 1.
Baseline demographic variables of the 5 cases with CD refractory to medications including anti-TNF-α therapies who were selected for this combination therapy with ADA plus intensive GMA
| Demography | Number of patients |
|---|---|
| Male/female | 4/1 |
| Age, years | 36 ± 17 |
| Mean disease duration, years | 8.5 ± 5.1 |
| Involved intestinal segment | |
| Ileocolitis | 1 |
| Colitis | 4 |
| Previous bowel resection | 1 |
| Perianal fistula | 1 |
| Concurrent medication | |
| Corticosteroids | 3 |
| Mesalamine/sulfasalazine | 4 |
| Metronidazole | 1 |
| Azathioprine | 1 |
| Infliximab | 1 |
| Adalimumab | 1 |
| Baseline CDAI | 324 ± 118 |
| Baseline CRP, mg/dl | 4.9 ± 3.3 |